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JBEI-7474
STRAINStrain E. Coli SmP CH184 (W3110 derivative). Called "pseudostreptomycin dependent strain".. SmP ribosomes contain mutations in protein S12 of their decoding center. In the absence of Sm, bacteria harboring these ribosomes display a “hyperaccurate” phenotype,with considerable reduction in translation rates (∼5 aa/s) and ∼20-fold increase in the accuracy of amino acid incorporation compared to wild type.. Such strain increase soluble fractions of total protein by promoting co-translational folding of individual domains.
- Institution
- JBEI
- ICE ID
- JPUB_007094
- Creator
- Jingwei Zhang
- TG Entity Type
- Microbrial-Strain
- TeselaGen ID
- bdd93a5e-e23e-4237-9f22-8550eab6a776
- Tag
- Zhang et al. 2016
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